He began his training in the workshop of his father Vittorio, a carpenter; thanks to the help of the poet Mario Rivosecchi in 1930 he moved to Rome, where he studied at the free school of the nude.
In 1931 he won the competition for a monument to Cardinal Dusmet (which he never realized); in 1932 and 1933 he took part in the competition for the National Artistic Pensioner, obtaining a scholarship, which he won thanks to the high relief from the ark. In 1933 he exhibited with Alberto Ziveri and Giuseppe Grassi at the Dario Sabatello gallery; in 1934 he exhibited in Paris the Portrait of Anita which was bought by the Museo Jeu de Paume.
In 1935 he took part in the II Quadrennial in Rome obtaining a prize for the Danza e Tempesta high-reliefs. He exhibited successfully again in Paris and Rome and in 1938 he opened his own studio in Via Margutta, where he remained for a lifetime. Participates in the Venice Biennale with different sculptures (Portrait of Ungaretti, Young who declaims, Young who listens). Participates in Corrente, Milanese art magazine that collects the main Italian artists and participates in the second exhibition of the movement.
In 1940 he married Anita Buy, then he left for military service in Zara, doing drawings for the magazines Primato, Documento, Domus. Back in Rome in 1943 he sculpts the Boy with the seagulls; The shotgun is instead inspired by the war climate.
In 1947 he won the Turin Prize with the Anita standing and participated in the exhibition of the New Front for the Arts, with Emilio Vedova, Renato Guttuso. In 1949 he won the Saint Vincent Prize with the opera Sibilla and participated in the Twentieth-Century Italian Art exhibition at the MoMa in New York . In 1951 he held his first anthology at the Fondazione Roma Prize; in 1952 he exhibited in New York; he returned to the Venice Biennale in 1954, winning the first prize for sculpture. In 1955 he began teaching at the Academy of Florence, while from 1958 until 1980 he taught at the Academy of Fine Arts in Rome.
Between the end of the fifties and the sixties he worked on impressive monumental projects not always realized: portal of the church of San Giovanni Battista on the A1; Fountain for the ENI Palace in Rome, Monument for the Resistance in Ancona, Monument to Kennedy (never realized, the sketch is in Grottammare, in the square that bears the artist's name). Since the forties, he was a frequent visitor to the Mass of the Artists in Piazza del Popolo in Rome, and a friend of his founder, Mons. Ennio Francia.
In 1961 he exhibited in Darmstadt; in 1962 in Düsseldorf, in 1963 the first of many exhibitions in Japan. In 1970 he began the "Resurrection" for the Sala Nervi at the Vatican, and contacts with Pope Paul VI led him to inaugurate his most famous work on 28 September 1977.
Two important anthologies retrace his career: in Avezzano in 1983 and at the National Gallery of Modern and Contemporary Art in 1984.
He died in Rome on December 4, 1987.
Pericle Fazzini is one of the biggest and most famous exponents of international sculpture. His works are preserved in major private collections and in the most important museums in the world including the Hakone open air museum in Japan, the Peggy Guggenheim Collection in Venice, the Tate Gallery in London, the National Gallery of Modern Art in Rome, the Art Institute of Chicago, the Momat of Tokyo and the Museum of Contemporary Art in Montréal. After his death there were numerous retrospectives dedicated to him and realized in museums and prestigious public spaces, such as the Setagaya art Museum in Tokyo, the splendid setting of the stones of Matera, Villa d'Este of Tivoli and the Sacred Heart in Paris. Among his closest students Vito Pancella (1945-2005) and currently in business Gino Giannetti.